What do I have to book before I fly to Italy?

Four things genuinely sell out: the Last Supper in Milan, the Borghese Gallery in Rome, the Vatican Museums in season, and the Colosseum's underground and arena floor tickets. Add the Uffizi and Florence's Duomo dome climb in summer. Everything else — most churches, most museums, most towns — you can decide on the day. Book the sell-outs the moment your dates are fixed, then build the days around them, because these are timed entries you cannot move. Restaurants for special evenings are the other thing worth booking from home.

This one changes. Last checked August 13, 2026 — confirm it close to your trip.